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Episodes
Interviews with people doing interesting things in pathology and related fields
Episodes
Monday Nov 04, 2024
Monday Nov 04, 2024
My guest today is Jon Odle from Pramana.
What we discuss with Jon:
- Overview of Pramana and its scanning technology
- Importance of QA/QC in digital pathology
- Challenges in scaling digital pathology, including labor costs
- The role of AI in digital pathology and its potential as a diagnostic aid
- The concept of Digital Pathology as a Service (DPAAS)
- Advantages of DPAAS, including cost-effectiveness and reduced labor
- The Mayo Clinic project to digitize 12 million slides
- Challenges faced during the Mayo project, including slide quality issues
- The importance of interoperability and standardization in digital pathology
- Future plans for Pramana
Links for this episode:
Inside the Digitization of Mayo Clinic's Tissue Registry Archive
People of Pathology Podcast:
Monday Sep 23, 2024
Monday Sep 23, 2024
My guest today is Pathologist Dr Emily Volk.
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Mentorship played a significant role in her career, guiding her decisions and shaping her path.
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Dr. Volk became involved with the College of American Pathologists (CAP) through a mentor, who encouraged her to join the cytopathology committee.
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Dr. Volk was elected to the CAP Board of Governors and later became the president, serving during the COVID-19 pandemic.
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Key accomplishments during her presidency included establishing the Council on Informatics and Pathology Innovation (CIPI) and navigating the implications of the Dobbs decision on pathology practice.
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She emphasizes the importance of pathologists as advocates for patients and the need to communicate effectively about pathology reports.
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Dr. Volk has started creating short videos on social media to educate patients and share leadership insights, inspired by a friend in the business world.
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She discusses the concept of "first do no harm" in leadership, advocating for thoughtful responses rather than rushing to action.
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Dr. Volk shares a personal story about her father's reaction to her language in one instance, emphasizing the importance of treating patients with respect and dignity.
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She addresses concerns about a study linking tattoos to lymphoma, highlighting the difference between association and causation in medical research.
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Dr. Volk believes it is crucial for pathologists to continue promoting their field and educating patients about the role of pathologists in their care.
Links for this episode:
Dr Emily Volk on Instagram
College of American Pathologists
Council on Informatics and Pathology Innovation
People of Pathology Podcast:
Monday Sep 02, 2024
Monday Sep 02, 2024
Dr Allison Goldberg is a cytopathologist, and Director of the Cytopathology Fellowship at Thomas Jefferson University.. What we discuss with Dr Goldberg:
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How her father's work in pharmaceutical industry on AIDS medications helped to inspire her career path
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How she found satisfaction in surgical procedures and the operating room environment initially
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Inspired by a conversation with a pathologist mom she made the transition to pathology
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How she tailors fellowship experiences based on goals and backgrounds of individual fellows
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Impact of AI in Pathology, including assisting in tasks like identifying specific cells and estimating percentages
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AI may not replace pathologists but can enhance certain aspects of pathology
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Importance of Leadership Roles in Pathology
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Pathologists should advocate for patient care and be involved in decision-making processes
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Personalized medicine and molecular testing advancements
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Emphasizing lifelong learning and curiosity to adapt to upcoming changes in the field
Links for this episode:
LabVine Laboratory Transformation Seasonal School
Thomas Jefferson University Cytopathology Fellowship Program
People of Pathology Podcast:
Monday Aug 26, 2024
Monday Aug 26, 2024
Nathan Buchbinder from Proscia returns to discuss Proscia's Precision Medicine AI Portfolio.
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The portfolio includes leading AI applications available on the Concentriq platform.
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The portfolio streamlines the process of deploying, supporting, and using AI applications in pathology.
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The portfolio includes applications from Proscia and other developers, including Ibex, Visiopharm, Stratipath, DoMore Diagnostics, Mindpeak, Nucleai.
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Collaboration with other vendors and developers is important to address the variety of AI applications needed and helps streamline the process.
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Multi-AI workflows on Concentriq enable the simultaneous use of multiple AI applications on a single image or work list.
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The Precision Medicine AI portfolio supports analysis of various tissue types, with a growing portfolio.
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The partnership with Nucleai enhances the functionality of Concentriq by incorporating AI biomarkers.
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Proscia's is focused on expanding the Precision Medicine AI portfolio, making platform enhancements, and adding new functionality.
Proscia is not the legal manufacturer of the products available in its precision medicine AI portfolio and pipeline. Certain products may only be available for diagnostic use in select geographies. Please contact Proscia for availability of an application in your geography.
Multi-AI workflows are available on Concentriq AP. Concentriq AP is for research use only. Not for use in diagnostic procedures.
Links for this episode:
Labvine Laboratory Transformation Seasonal School
Concentriq AP: A New Era of AI in Pathology Webinar
People of Pathology Podcast:
Monday Aug 19, 2024
Monday Aug 19, 2024
Dr Denise Gemmellaro is a forensic entomologist, and my guest today.
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We discuss how she initially pursued medical school but found it was not for her.
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She found forensic entomology to be a complete and engaging field that allowed her to work on real cases and teach.
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Dr. Gemmellaro emphasized the importance of students realizing they can change their career path and explore different avenues.
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Forensic entomology involves the study of insects and arthropods in medico-legal investigations, providing valuable information on the circumstances of death and post-mortem events.
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In entomotoxicology, substances found in maggots can indicate what was present in the body prior to death, aiding in toxicology analysis.
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Dr. Gemmellaro has conducted training for law enforcement in forensic entomology, emphasizing the importance of proper evidence collection and handling.
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She has also been involved in international projects in Africa and Central America to introduce forensic science and inspire local professionals in the field.
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Dr. Gemmellaro encourages those interested in forensic entomology to explore entomology programs and resources, as well as consider related fields like law enforcement or lab technician roles.
Links for this episode:
Dr Denise Gemmellaro email
American Board of Forensic Entomology
The ESA (Entomological Society of America)
ESA pages listing the entomology programs in the US:
and here
People of Pathology Podcast:
Monday Aug 05, 2024
Monday Aug 05, 2024
Today Dr Ritcha Saxena returns to the podcast.
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She integrated virtual teaching methods into her educational approach, including online lectures, Zoom discussions, and virtual microscopy.
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Dr. Saxena was involved in a study analyzing pathology education in medical schools in the U.S. and other countries, focusing on curriculum content, teaching methods, and instructional time allocation.
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The study showed differences in pathology education between the U.S. and other countries, with more lecture hours and active learning strategies outside the U.S.
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We discuss the 2010 Carnegie Foundation report on medical education reform, emphasizing integration of basic sciences with clinical training and active learning strategies.
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She is currently working on integrating pathology into interprofessional education and writing a manual on AI's impact on medical education.
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Dr. Saxena is dedicated to promoting diversity, equity, and inclusion in healthcare education and has received recognition for her contributions in this area.
Links for this episode:
People of Pathology Podcast:
Monday Jul 29, 2024
Monday Jul 29, 2024
Jacob Guggenheim is head of engineering at Vistapath. Their innovative Sentinel is bringing AI to specimen grossing.
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Jacob's background in bioengineering and robotics led him to join Vistapath
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Vistapath's mission is to improve the efficiency and accuracy of the histology process, inspired by a real-world incident
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The Sentinel is designed to augment human capabilities in grossing specimens, not replace humans
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An accomplishment Jacob is proud of is the impact of the Sentinel in providing confidence to grossing technicians through photographic evidence
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The future of Vistapath includes expanding the capabilities of the Sentinel to gross a wider range of tissue and leveraging data collected during grossing for downstream processes
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AI is already transforming pathology, but the data bottleneck is a significant barrier that needs to be addressed for further impact
Links for this episode:
People of Pathology Podcast:
Monday Jul 01, 2024
Monday Jul 01, 2024
My guests today are Dr Simone Arvisais-Anhalt and Dr Daniel Qazi.
- We discussed the benefits of using LLMs in pathology, including creating outlines, data analysis, and translating reports for patients
- There are also challenges in the use LLMs, such as hallucinations and bias
- Dr. Arvisais-Anhalt and Dr. Qazi described their study on using LLMs in clinical practice
- They were some interesting findings from the study, including different use cases and limitations of the tool
- We talked about future plans to implement retrieval augmented generation for tailored responses in pathology and laboratory medicine
Links for this episode:
What is Retrieval Augmented Generation?
People of Pathology Podcast:
Monday Jun 10, 2024
Monday Jun 10, 2024
Jospeh Mossel co-founded Ibex in 2016. Since its inception, Ibex has remained committed to developing AI applications for clinical diagnostics.
The company achieved its first milestone in 2018 by deploying its first algorithm for prostate cancer. This algorithm not only enhanced diagnostic efficiency but also detected a diagnostic error, demonstrating the value of AI in pathology.
Over the years, IBEX has expanded its offerings to include algorithms for breast and gastric cancers, facing challenges due to the unique characteristics of each tissue type. However, through partnerships with healthcare organizations and pharmaceutical companies, IBEX has continued to innovate and grow.
This conversation covers the history of Ibex and some of their milestones. We conclude with a look toward the future of AI in pathology.
Links for this episode:
People of Pathology Podcast:
Monday Jun 03, 2024
Monday Jun 03, 2024
My guests today are Imogen Fitt from Signify Research and Nathan Buchbinder from Proscia. We discuss emerging trends in pathology, including:
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The current technology with the most significant impact in the field of pathology has been artificial intelligence (AI).
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AI has stirred up imaginations about the future of pathology and has accelerated the timeline for seeing its impact.
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Return on investment in digital pathology has shifted from being a challenge to becoming an opportunity that drives adoption.
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Pathologists are not being replaced by AI but rather augmented by it to make their work easier and more efficient.
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Precision medicine is a key emerging trend in pathology, with a focus on clinical biomarkers, companion diagnostics, and personalized treatment pathways.
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Telepathology plays a crucial role in improving access to pathology services, especially in underserved areas and remote locations.
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Collaboration among digital pathology companies is driven by customer demand for interoperability and seamless integration of technologies.
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The future of pathology technology is likely to focus on precision medicine, clinical biomarkers, companion diagnostics, digital pathology storage, compression algorithms, robotics, and value-based care.
Links for this episode:
People of Pathology Podcast: